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Algidisides I and II, New Iridoid Glycosides from Gentiana algida
Chem Nat Compd Chemistry of Natural Compounds
Format: Journal Article
Publication Date: Nov 30, 2015
Pages: 637 - 641
Sources ID: 103591
Visibility: Public (group default)
Abstract: (Show)
Two new iridoid glycosides, algidiside I [2′-(2′′,3′′-dihydroxybenzoyl)loganic acid] (1) and algidiside II [6′-(2′′,3′′-dihydroxybenzoyl)loganic acid] (2), and 14 known iridoids including for the first time from the aerial part of Gentiana algida Pall. 2′-(2′′,3′′-dihydroxybenzoyl)swertiamarin and the 6′-O-β-D-glucosides of loganic acid and swertiamarin were isolated. Compounds 1 and 2 showed pronounced anti-inflammatory activity in the 12-O-tetradecanoylphorbol-acetate-induced inflammation model. HPLC found that the iridoids were distributed organ-specifically in the aerial part of G. algida.