The Government of India, under Prime Minister Shri Narendra Modi has emphasised increased advocacy of AYUSH system of medicine and establishment of Indian systems of medicine specialty centres. Taking this vision forward, the Rashtrapati Bhavan with help of Ministry of AYUSH, Government of India; established the first AYUSH Wellness Clinic (AWC) of the country with all the five systems under one roof at Presidents Estate in July 2015. AWC caters to the medical needs of the President, officials of Presidents Secretariat and residents of the Presidents Estate. The mission of AWC is achieving and maintaining excellence in healthcare services through Indian system of medicine and Homoeopathy. This paper presents the annual report of work done at AWC in the year 2017. A total of 33163 patients consulted and nearly 19000 received various therapies prescribed by the physicians. The yearly AYUSH awareness workshop for residents was conducted this year too with much success. As new initiative in the year 2017- new therapies were added to the existing services in Ayurveda wing, Yoga and Naturopathy wing and Unani wing; the therapists and support staffs working at AWC were trained in First-AID and CPR and 21 research papers were published in peer reviewed indexed journals.