Dr. Brecher is a clinical psychologist who uses cognitive behavioral strategies to buffer students against the pervasive depression and anxiety present in higher education. We talk about her science-informed recommendations, which include positive psychological activities designed to increase mindfulness, character strengths, self-efficacy, optimism, gratitude, and more. We discuss the mechanisms through which these interventions work, some of the many benefits they promote, how they can be implemented in schools, and some changes in academic culture that can improve student well-being.