Studied how a course in transcendental meditation (TM) affected the responses of 50 male and 50 female Ss to the Omnibus Personality Inventory (OPI) and how these responses compared with those of the normative sample (NS). The OPI was administered before and after the 22-day course. The TM students considered themselves less tense and anxious than the NS before the course, and even more relaxed afterward. Before the course the TM participants were more prone to "acting out" their feelings, more interested in social activities, and more liberal in religious orientation, than the NS; after the course they responded more like the NS, especially on the religious orientation subscale. TM Ss differed markedly from the NS, and did not change during the course, in being more imaginative, free-thinking, intellectually oriented, self-determining, considerate of others, and feminine. On the thinking introversion, personal integration, and response bias subscales, TM Ss were like the NS before the course, but afterward had higher scores than the NS. The limitations of the study are discussed.