Effects of yoga on cancer-related fatigue and global side-effect burden in older cancer survivors
Journal of geriatric oncology
Short Title: J.Geriatr.Oncol.
Format: Journal Article
Publication Date: Nov 30, 2014
Pages: 8 - 14
Sources ID: 29766
Notes: LR: 20170220; CI: Copyright (c) 2014; GR: R01 CA181064/CA/NCI NIH HHS/United States; GR: U10CA037420/CA/NCI NIH HHS/United States; GR: K07 CA168911/CA/NCI NIH HHS/United States; GR: R25CA102618/CA/NCI NIH HHS/United States; GR: K07 CA120025/CA/NCI NIH HHS/United States; GR: UG1 CA189961/CA/NCI NIH HHS/United States; GR: U10 CA037420/CA/NCI NIH HHS/United States; GR: K07CA120025/CA/NCI NIH HHS/United States; GR: R25 CA102618/CA/NCI NIH HHS/United States; GR: KL2 TR000095/TR/NCATS NIH HHS/United States; JID: 101534770; NIHMS640488; OTO: NOTNLM; 2014/06/09 00:00 [received]; 2014/08/26 00:00 [revised]; 2014/09/22 00:00 [accepted]; 2014/12/03 06:00 [entrez]; 2014/12/03 06:00 [pubmed]; 2015/09/15 06:00 [medline]; ppublish
Collection: Yoga-Based Medical Interventions
Visibility: Public (group default)
BACKGROUND: Sixty percent of cancer survivors are 65years of age or older. Cancer and its treatments lead to cancer-related fatigue and many other side effects, in turn, creating substantial global side-effect burden (total burden from all side effects) which, ultimately, compromises functional independence and quality of life. Various modes of exercise, such as yoga, reduce cancer-related fatigue and global side-effect burden in younger cancer survivors, but no studies have specifically examined the effects of yoga on older cancer survivors. OBJECTIVES: The purpose of this study was to assess the effects of a 4-week yoga intervention (Yoga for Cancer Survivors: YOCAS(c)(R)) on overall cancer-related fatigue, and due to its multidimensional nature, the subdomains of cancer-related fatigue (general, physical, emotional, and mental) and global side-effect burden in older cancer survivors. MATERIALS AND METHODS: We conducted a secondary analysis on data from a multicenter phase III randomized controlled clinical trial with 2 arms (standard care and standard care plus a 4-week YOCAS(c)(R) intervention). The sample for this secondary analysis was 97 older cancer survivors (>/=60years of age), between 2months and 2years post-treatment, who participated in the original trial. RESULTS: Participants in the YOCAS(c)(R) intervention arm reported significantly lower cancer-related fatigue, physical fatigue, mental fatigue, and global side-effect burden than participants in the standard care arm following the 4-week intervention period (p<0.05). CONCLUSIONS: YOCAS(c)(R) is an effective standardized yoga intervention for reducing cancer-related fatigue, physical fatigue, mental fatigue, and global side-effect burden among older cancer survivors.