This article provides a general profile of the Mind and Life Institute, a group established by His Holiness the Dalai Lama and Western scientists to pursue the interface between Buddhism and science through dialogue and collaborative research projects. This article Includes comments from many of the key members describing the history and goals of the institute, as well as current and future activities. Also featured are profiles of Richard Davidson, a neuroscientist from the University of Wisconsin, Paul Ekman, an expert on emotions and facial expressions, and Steven Chu, a Nobel laureate in physics and a participant in the 2002 Mind and Life Conference "Matter, Physics, and Buddhism." (Zach Rowinski 2004-05-17)