In 1979, a molecular biologist, Jon Kabat-Zin set up a clinic at the University of Massachussets Medical School where he taught Mindfulness-Based Stress Reduction (MBSR) to people suffering from chronic pain and the stress of living with chronic illness. Kabat-Zin built this course out of a combination of Zen meditation, Vipassana from Theravada Buddhism and yoga but it was taught in secular language to make it accessible to this new audience.Mindfulness meditation involves consciously paying attention to sensory experience from moment-to-moment. When the mind wanders and becomes absorbed in thinking, attention is redirected to sensations. This develops acceptance of what takes place in subjective experience and awareness of the way the mind becomes distracted. The practice enables a person to better understand and accept patterns of thoughts, emotions and feelings rather than react automatically to changing conditions. During the 1990’s, three clinical psychologists, Jon Teasdale, Zindel Segal and Mark Williams, became interested in the potential for meditation as a new treatment to prevent depression. MBSR was the right fit as it was a repeatable programme, taught in secular language and previously delivered in a medical environment. They called their course, Mindfulness-based Cognitive Therapy (MBCT) and so, with this work, mindfulness meditation gained a scientific foundation. An explosion of interest in mindfulness as a therapy, self-help and in the workplace has followed. This article discusses how Buddhism paired with pragmatism can provide positive impact on social change toward a more humane organizational culture.