A review of the literature reveals that one particular form of mindful practice, mindfulness, has received the most research attention during the past decade. While all of this attention has been focused on mindfulness, the clinical usefulness of other mindful practices has been ignored. Built upon this background, the purpose of this article is to bring attention to an overlooked form of mindful practice that grows out of the Christian tradition: Centering Prayer. The article begins with a description of Centering Prayer, along with a comparison with mindfulness. The remainder of the article explores the clinical implications of Centering Prayer. First, ways in which Centering Prayer informs our understanding of the need for and the goals of counseling are suggested. Next, four therapeutic skills of Centering Prayer, along with three distinct ways for integrating Centering Prayer into psychotherapy are offered. Throughout the clinical section of the article, numerous practical ideas and strategies are developed. Finally, a case study is included to illustrate the potential benefits of including Centering Prayer in psychotherapy.