BACKGROUND: In the case of pulpitis the dentist has to differentiate between a reversible and therefore treatable pulpal inflammation and an irreversible damage of the pulpa, accord-ing to the clinical symptoms. From these one cannot draw conclusions about the effective histological condition of the pulpa. Early stages of pulpitis cannot be recognized by X-rayeither.OBJECTIVES: By means of case studies in the course of daily dental practice the following questions are addressed:Is dental pulpitis an indication for the use of the Tibetan remedy Padma 28? Can a root canal treatment be prevented by administering Padma 28? What dosage is appropriate in this indication? PATIENTS AND METHODS: 53 patients with symptoms of chronic dental pulpitis but without clear indication for an im-mediate root canal treatment were prescribed 2 x 2 tablets Padma 28 daily, for 15 days. 49 patients took the preparation,and the course of symptoms was recorded and analyzed according to a simple scheme. RESULTS: 27 of these patients(55%) were free of pain within 1 month. A total of 40 patients(81%) reached a pain-free state after a longer period. By now, in most cases observations have been made for a period of 2-3 years (maximum: 5.5 years). 12 patients (24%) remained without relapse so far for more than 3 years. These experiences allow to deduce possible indications and clinical symptoms for the use of Padma 28. CONCLUSIONS: These results en-courage the use of Padma 28 as a complementary preparation with little side effects, in unclear cases of pulpitis. The clinical development can be observed without further treatment if the patient does not need pain medication. Most patients (>80%) showed a complete remission, positively affect-ed and expedited by Padma 28; root canal treatments or ex-tractions could be prevented. In many cases the improvement has sustained over observation periods of >3 years. Criteria for therapeutic decisions are proposed.