A resilience intervention involving mindfulness training for transplant patients and their caregivers
Short Title: Clin.Transplant.
Format: Journal Article
Publication Date: Nov 30, 2015
Pages: 1466 - 1472
Sources ID: 29671
Notes: LR: 20180430; CI: (c) 2016; JID: 8710240; OTO: NOTNLM; 2016/08/30 00:00 [accepted]; 2016/11/03 06:00 [pubmed]; 2018/01/19 06:00 [medline]; 2016/09/13 06:00 [entrez]; ppublish
Collection: Yoga-Based Medical Interventions
Visibility: Public (group default)
Solid organ and stem cell transplant patients and their caregivers report a substantial level of distress. Mindfulness-based stress reduction has been shown to alleviate distress associated with transplant, but there is limited experience in this population with other mindfulness-based interventions, or with combined transplant patient and caregiver interventions. We evaluated a novel, 6-week mindfulness-based resilience training (MBRT) class for transplant patients and their caregivers that incorporates mindfulness practice, yoga, and neuroscience of stress and resilience. Thirty-one heart, liver, kidney/pancreas, and stem cell transplant patients and 18 caregivers at Mayo Clinic in Arizona participated. Measures of stress, resilience, depression, anxiety, health-related quality of life, positive and negative affect, and sleep were completed at baseline, 6 weeks, and 3 months postintervention. At 6 weeks and 3 months, patients demonstrated significant (P<.005) improvements from baseline in measures of perceived stress, depression, anxiety, and negative affect. Quality-of-life mental component (P=.006) and positive affect (P=.02) also improved at follow-up. Most participants adhered to the program, were satisfied with class length and frequency, and reported improved well-being as a result of the class. MBRT holds promise as an intervention to enhance resilience and manage stress for transplant patients and their caregivers.