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A Systematic Review of Mechanisms of Change in Body-Oriented Yoga in Major Depressive Disorders
Short Title: Pharmacopsychiatry
Format: Journal Article
Publication Date: Nov 30, 2017
Pages: 73 - 81
Sources ID: 31376
Notes: LR: 20180917; CI: (c) Georg Thieme Verlag KG Stuttgart . New York.; JID: 8402938; 0 (Brain-Derived Neurotrophic Factor); 7171WSG8A2 (BDNF protein, human); WI4X0X7BPJ (Hydrocortisone); 2017/06/02 06:00 [pubmed]; 2018/09/18 06:00 [medline]; 2017/06/02 06:00 [entrez]; ppublish
Visibility: Public (group default)
Abstract: (Show)
INTRODUCTION: Despite empirical evidence for the efficacy of body-oriented yoga as add-on treatment for major depressive disorder (MDD), the specific mechanisms by which yoga leads to therapeutic changes remain unclear. By means of a systematic review, we evaluate how the field is progressing in its empirical investigation of mechanisms of change in yoga for MDD. METHODS: To identify relevant studies, a systematic search was conducted. RESULTS: The search produced 441 articles, of which 5 were included, that empirically examined 2 psychological mechanisms (mindfulness, rumination) and 3 biological mechanisms (vagal control, heart rate variability [HRV], brain-derived neurotrophic factor [BDNF], cortisol). 2 studies found that decreased rumination and 1 study that increased mindfulness was associated with the effect of yoga on treatment outcome. In addition, preliminary studies suggest that alterations in cortisol, BDNF, and HRV may play a role in how yoga exerts its clinical effect. DISCUSSION: The results suggest that body-oriented yoga could work through some of the theoretically predicted mechanisms. However, there is a need for more rigorous designs that can assess greater levels of causal specificity.