Two new compounds, Talaromycin A and B, isolated from an endophytic fungus, Talaromyces aurantiacus
Natural Product Research
Short Title: Nat. Prod. Res.
Format: Journal Article
Publication Date: 2019/03/31/
Pages: 1 - 7
Sources ID: 95201
Collection: Himalayan and Tibetan Medicine
Visibility: Public (group default)
Two new compounds Talaromycin A (1) and Talaromycin B (2) were isolated from a liquid culture of Talaromyces aurantiacus. The structures of 1 and 2 were elucidated by IR, MS, 1D and 2D NMR spectra and comparison of the experimental and calculated electronic circular dichroism spectra. Additional known compounds (3-6) were also isolated. These compounds were tested for monoamine oxidase, acetylcholinesterase and PI3K inhibitory activity, but showed only weak activity.