Chemical constituents from the aerial parts of Codonopsis nervosa
CJNM Chinese Journal of Natural Medicines
Format:
Journal Article
Publication Date:
Nov 30, 2011
Pages:
366 - 369
Sources ID:
103486
Collection:
Himalayan and Tibetan Medicine
Visibility:
Public (group default)
Abstract:
(Show)
To study the chemical constituents of the aerial parts of Codonopsis nervosa (Chipp.) Nannf. (Campanulaceae), a commonly used Tibetan herb. The constituents were isolated by D-101 porous polymer resin, silica gel, ODS and Sephadex LH-20 column chromatography, and their structures were elucidated on the basis of spectroscopic analysis. 15 compounds were isolated and identified as chrysoeriol (1 ), tricin (2 ), apigenin (3 ), succinic acid (4) ,β -sitosterol-3-O-β -D-glucopyranoside (5 ), luteolin (6 ), luteolin-7-O-β- D-glucopyranoside (7 ), ethylsyringin (8 ), apigenin-7-O-β -D-glucopyranoside (9 ), luteolin-7-O-β- D-glucopyranosyl- (1→6)-[6′′′-O -caffeoyl]-β -D-glucopyranoside (10 ), luteolin- 7-O-β- D-gentiobioside (11 ), syringin (12 ), 3-O- caffeoylquinic acid (13 ), 5-O- caffeoylquinic acid (14) , and 4-O -(β- D-glucopyranosyl)-benzoic acid (15) , respectively. Compounds 1-5, 8, 9, 12, 14, 15 were reported from C. nervosa for the first time.