Effectiveness of Honghua Ruyi Wan combined with antibiotics for relief of pelvic inflammatory disease pain in women.
Biomedical Research (0970-938X)
Short Title:
Biomedical Research (0970-938X)
Format:
Journal Article
Publication Date:
2017/11/20/
Pages:
4665 - 4670
Sources ID:
93846
Notes:
Accession Number: 123606316; Dai Zhang 1 Zhaohui Liu 1 Huaixian Lin 1 Qinping Liao 1 Shuxia Li 2 Long Sui 3 Zhengai Xiong 4 Dikai Zhang 5 Shuzhen Dai 6; Affiliation: 1: Department of Obstetrics and Gynecology, the First Hospital of Peking University, Beijing 100034, PR China 2: Department of Obstetrics and Gynecology, Tianjin Central Hospital, Tianjin 300000, PR China 3: Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200001, PR China 4: Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, PR China 5: Department of Obstetrics and Gynecology, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou 510655, PR China 6: Department of Obstetrics and Gynecology, the Affiliated Hospital of Qingdao University, Qingdao 266000, PR China; Source Info: 2017, Vol. 28 Issue 10, p4665; Subject Term: ANTIBIOTICS; Subject Term: PELVIC inflammatory disease treatment; Subject Term: PELVIC pain treatment; Subject Term: BLIND experiment; Subject Term: TREATMENT effectiveness; Subject Term: HERBAL medicine; Author-Supplied Keyword: Honghua Ruyi Wan (HHRYW); Author-Supplied Keyword: Pelvic inflammatory disease; Author-Supplied Keyword: Relieve abdominal pain; Author-Supplied Keyword: Tibetan medicine; NAICS/Industry Codes: 414510 Pharmaceuticals and pharmacy supplies merchant wholesalers; NAICS/Industry Codes: 325411 Medicinal and Botanical Manufacturing; NAICS/Industry Codes: 424210 Drugs and Druggists' Sundries Merchant Wholesalers; NAICS/Industry Codes: 325410 Pharmaceutical and medicine manufacturing; Number of Pages: 6p; Document Type: Article
Collection:
Himalayan and Tibetan Medicine
Visibility:
Public (group default)
Abstract:
(Show)
Honghua Ruyi Wan (HHRYW) is a traditional Tibetan drug. We designed this study to investigate the effectiveness of HHRYW for relief of pelvic inflammatory disease (PID) pain in women. We performed a multicenter, randomized, double-blind, placebo-controlled trial, and observed the effectiveness and toxicity of HHRYW in combination with moxifloxacin in treating PID. Of the 139 women enrolled in this study, 124 were included in the final analysis. They were divided into the HHRYW group (n=65) and the placebo group (n=59). The baseline age, height, weight, and marital status were well matched between the groups (all: P>0.05). The rate of reduction in tenderness score was significantly greater in the HHRYW group than in the placebo group after 30, 60, and 90 days of treatment. The HHRYW group had a significantly lower subjective visual analogue scale score at 30, 60, and 90 days after treatment. The incidence of adverse reactions was 7.04% (5/71) in the HHRYW group and 10.61% (7/59) in the placebo group. No severe adverse reactions were noted in either group. The combination of HHRYW and antibiotics effectively relieve abdominal pain caused by PID with obvious long-term efficacy and acceptable adverse reactions. [ABSTRACT FROM AUTHOR]