Essential Oil Composition and Bioactivities of Waldheimia glabra (Asteraceae) from Qinghai-Tibet Plateau
Molecules
Short Title:
Molecules
Format:
Journal Article
Publication Date:
2017/03//
Pages:
460
Sources ID:
93731
Notes:
Accession Number: 122142158; Ji De 1; Email Address: 12110700018@fudan.edu.cn Yan Lu 2; Email Address: luyan@fudan.edu.cn Lijun Ling 2; Email Address: 13111030032@fudan.edu.cn Nan Peng 3; Email Address: nanpeng@fudan.edu.cn Yang Zhong 3; Email Address: yangzhong@fudan.edu.cn; Affiliation: 1: College of Science, Tibet University, Lhasa 8500, Tibet, China 2: School of Pharmacy, Fudan University, Shanghai 201203, China 3: School of Life Science, Fudan University, Shanghai 200438, China; Source Info: Mar2017, Vol. 22 Issue 3, p460; Subject Term: ESSENTIAL oils; Subject Term: GAS chromatography/Mass spectrometry (GC-MS); Subject Term: INFLUENZA treatment; Subject Term: CARYOPHYLLENE; Subject Term: ANTI-inflammatory agents; Author-Supplied Keyword: anti-inflammatory; Author-Supplied Keyword: anti-influenza; Author-Supplied Keyword: essential oil; Author-Supplied Keyword: Tibetan medicine; Author-Supplied Keyword: Waldheimia glabra; NAICS/Industry Codes: 325998 All Other Miscellaneous Chemical Product and Preparation Manufacturing; NAICS/Industry Codes: 325999 All other miscellaneous chemical product manufacturing; NAICS/Industry Codes: 418410 Chemical (except agricultural) and allied product merchant wholesalers; NAICS/Industry Codes: 424690 Other Chemical and Allied Products Merchant Wholesalers; Number of Pages: 7p; Illustrations: 2 Charts, 1 Graph; Document Type: Article
Collection:
Himalayan and Tibetan Medicine
Visibility:
Public (group default)
Abstract:
(Show)
Waldheimia glabra is traditionally used as incense and as an anti-influenza drug by Tibetans in China. Here, we collected W. glabra from the Gangs Rinpoche mountain at an altitude of 5200 m, and analyzed its essential oil by gas chromatography-mass spectrometry (GC-MS) combined with the retention indices (RI). Twenty-seven compounds, representing 72.4% of the total essential oil, were identified, including α-bisabolol (20.2%), valeranone (11.8%), chamazulene (9.9%), spathulenol (8.2%), β-caryophyllene (6.1%), and caryophyllene oxide (5.2%). Bioactivity evaluation of the essential oil revealed that it exhibited potent anti-influenza effect on viruses H3N2 and anti-inflammatory effect by inhibiting the lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 macrophages, but no anti-complementary activity.