This afterword considers both the commonalities and differences in the approaches to mindfulness described in these two special journal issues. The approaches can be divided into those derived from scientific analysis and those taking a more experiential-humanistic perspective. These two perspectives generate different therapeutic strategies, which appear to have the same underlying principle. The question of whether practitioners should have a personal mindfulness practice is then considered. It is suggested that mindfulness is a holistic intervention. Finally, there are some personal reflections on running mindfulness courses.