Two new compounds, Talaromycin A and B, isolated from an endophytic fungus, Talaromyces aurantiacus.
Natural product research
Format:
Journal Article
Publication Date:
Nov 30, 2018
Pages:
1 - 7
Sources ID:
106381
Collection:
Himalayan and Tibetan Medicine
Visibility:
Public (group default)
Abstract:
(Show)
Two new compounds Talaromycin A (1) and Talaromycin B (2) were isolated from a liquid culture of Talaromyces aurantiacus. The structures of 1 and 2 were elucidated by IR, MS, 1D and 2D NMR spectra and comparison of the experimental and calculated electronic circular dichroism spectra. Additional known compounds (3-6) were also isolated. These compounds were tested for monoamine oxidase, acetylcholinesterase and PI3K inhibitory activity, but showed only weak activity.