Global research on mind-body therapies is analysed, by focussing on scholarly articles on three Eastern disciplines (yoga, tai chi and qi gong) and three procedures (meditation, breathing exercises and relaxation). The bibliographic research was done using the Scopus database. The search was limited to the biomedical areas and to the years 2006-2010. We have analysed 2,363 articles published by 959 different journals. They were written by 6,583 authors from 2,162 institutions in 65 countries. Indicators of scientific productivity and impact were calculated for institutions, countries and subject areas, and the collaboration between authors and institutions was also determined. We have observed a progressive increase of publications, especially on yoga and meditation, particularly from universities in the US, India and China with a marked concentration in the areas of internal medicine, mental health and oncology.
How exactly does meditation affect your body?
For centuries, the egoism-altruism debate has echoed through Western thought. Egoism says that the motivation for everything we do, including our seemingly selfless acts of care for others, is to gain one or another self-benefit. Altruism, while not denying the force of self-interest, says that under certain circumstances we can care for others for their sakes, not our own. Over the past half-century, social psychologists have turned to laboratory experiments on humans to provide a scientific resolution of this debate about our nature. The experiments have focused on the possibility that empathic concern-other-oriented emotion elicited by and congruent with the perceived welfare of someone in need-produces altruistic motivation to remove that need. With carefully constructed experimental designs, these scientists have tested the nature of the motivation produced by empathic concern, determining whether it is egoistic or altruistic and, thereby, providing an answer to a fundamental question about what makes us tick. Framed as a detective story, this book traces the scientific search for altruism through numerous studies and attempts to examine various motivational suspects, reaching the improbable conclusion that empathy-induced altruism is indeed part of our nature. The book then considers the implications of this conclusion both for our understanding of who we are as humans (the bad news as well as the good) and for how we might create a more humane society.
Flexibility: Yoga moves simulating animal moves to excite the imagination while improving flexibility. Fun follow-along creative movement story for ages 3-7 that develops fitness, flexibility, and self-regulation skills. Kids get expert physical instruction and learn that everyone is different and special in their own way.
Features live, unrehearsed in-school assemblies with, Scott Cole, and children of all ages, with educational tips and insights on how to motivate, teach, and move children with mind/body exercise and life-enhancing philosophy, inspiring a lifetime of healthy choices. Research shows that yoga, tai chi, and healthy exercise help reduce ADHD (Attention Deficit Hyperactivity Disorder), while improving focus and overall health of children.
<p>The Scottish Centre for Himalayan Research unites staff from across Scotland in a collaborative and interdisciplinary area studies centre at the University of Aberdeen. They offer two taught postgraduate programmes, an MRes in Himalayan Studies and an MSc in Himalayan Ethnobotany. PhD research is possible in a wide range of fields and along the entire length of the Himalayas. Researchers draw on expertise and resources from all the Scottish universities. (from the Center's website)</p>
While working on a difficult case with some particularly difficult opposing council, Scott Rogers said he had a moment during a mindfulness sitting when he realized the way he was dealing with the matter of litigation wasn't reducing that quality of dissatisfaction with that experience, it was contributing to it. Rogers, who has written several books, now serves as the director of the Mindfulness in Law program at the University of Miami School of Law, working with law students and faculty to embrace mindfulness as a way to be less stressed, but still competitive in the field.
Chronic inflammation is associated with various chronic illnesses including immunity disorders, cancer, neurodegeneration, and vascular diseases. Iridoids are compounds with anti-inflammatory properties. However their anti-inflammatory mechanism remains unclear. Here, we report that scropolioside B, isolated from a Tibetan medicine (Scrophularia dentata Royle ex Benth.), blocked expressions of TNF, IL-1, and IL-32 through NF-κB pathway. Scropolioside B inhibited NF-κB activity in a dose-dependent manner with IC50 values of 1.02 μmol/L. However, catalpol, similar to scropolioside B, was not effective in inhibiting NF-κB activity. Interestingly, scropolioside B and catalpol decreased the expression of NLRP3 and cardiolipin synthetase at both the mRNA and protein level. Our results showed that scropolioside B is superior in inhibiting the expression, maturation, and secretion of IL-1β compared to catalpol. These observations provide further understanding of the anti-inflammatory effects of iridoids and highlight scropolioside B as a potential drug for the treatment of rheumatoid arthritis and atherosclerosis.
Chronic inflammation is associated with various chronic illnesses including immunity disorders, cancer, neurodegeneration, and vascular diseases. Iridoids are compounds with anti-inflammatory properties. However their anti-inflammatory mechanism remains unclear. Here, we report that scropolioside B, isolated from a Tibetan medicine (Scrophularia dentata Royle ex Benth.), blocked expressions of TNF, IL-1, and IL-32 through NF-κB pathway. Scropolioside B inhibited NF-κB activity in a dose-dependent manner with IC50 values of 1.02 μmol/L. However, catalpol, similar to scropolioside B, was not effective in inhibiting NF-κB activity. Interestingly, scropolioside B and catalpol decreased the expression of NLRP3 and cardiolipin synthetase at both the mRNA and protein level. Our results showed that scropolioside B is superior in inhibiting the expression, maturation, and secretion of IL-1β compared to catalpol. These observations provide further understanding of the anti-inflammatory effects of iridoids and highlight scropolioside B as a potential drug for the treatment of rheumatoid arthritis and atherosclerosis.
Chronic inflammation is associated with various chronic illnesses including immunity disorders, cancer, neurodegeneration, and vascular diseases. Iridoids are compounds with anti-inflammatory properties. However their anti-inflammatory mechanism remains unclear. Here, we report that scropolioside B, isolated from a Tibetan medicine (Scrophularia dentata Royle ex Benth.), blocked expressions of TNF, IL-1, and IL-32 through NF-κB pathway. Scropolioside B inhibited NF-κB activity in a dose-dependent manner with IC50 values of 1.02 μmol/L. However, catalpol, similar to scropolioside B, was not effective in inhibiting NF-κB activity. Interestingly, scropolioside B and catalpol decreased the expression of NLRP3 and cardiolipin synthetase at both the mRNA and protein level. Our results showed that scropolioside B is superior in inhibiting the expression, maturation, and secretion of IL-1β compared to catalpol. These observations provide further understanding of the anti-inflammatory effects of iridoids and highlight scropolioside B as a potential drug for the treatment of rheumatoid arthritis and atherosclerosis.
Erigeron multiradiatus (Lindl.) Benth is a traditional Tibetan medicine herb long used to treat various diseases related to inflammation. Our previous phytochemical studies on E. multiradiatus resulted in the isolation of scutellarin, which is a known flavone glucuronide with comprehensive pharmacological actions. In present study, we investigated the inhibition action of scutellarin on high glucose-induced vascular inflammation in human endothelial cells (ECV304 cells). Consistent with previous reports, exposure of ECV304 cells to high glucose for 24 h caused an increase of intercellular adhesion molecule-1 (ICAM-1) and monocyte chemoattractant protein 1 (MCP-1), and promoted cell adhesion between monocyte and ECV304 cells. However, pretreatment with scutellarin (0.1 and 1 microM) reversed these effects in a concentration-dependent manner. Scutellarin was able to inhibit the activation of NF-kappaB induced by high glucose in ECV304 cells. Furthermore, although oral administration of scutellarin (10 and 50 mg/kg) did not produce significant antihyperglycemic action, it lowered the serum MCP-1 levels significantly in alloxan-induced diabetic mice. Therefore, our results suggest that scutellarin has anti-inflammation effect that may afford some protection against hyperglycemia-induced vascular inflammatory both in vitro and in vivo.
Erigeron multiradiatus (Lindl.) Benth is a traditional Tibetan medicine herb long used to treat various diseases related to inflammation. Our previous phytochemical studies on E. multiradiatus resulted in the isolation of scutellarin, which is a known flavone glucuronide with comprehensive pharmacological actions. In present study, we investigated the inhibition action of scutellarin on high glucose-induced vascular inflammation in human endothelial cells (ECV304 cells). Consistent with previous reports, exposure of ECV304 cells to high glucose for 24 h caused an increase of intercellular adhesion molecule-1 (ICAM-1) and monocyte chemoattractant protein 1 (MCP-1), and promoted cell adhesion between monocyte and ECV304 cells. However, pretreatment with scutellarin (0.1 and 1 microM) reversed these effects in a concentration-dependent manner. Scutellarin was able to inhibit the activation of NF-kappaB induced by high glucose in ECV304 cells. Furthermore, although oral administration of scutellarin (10 and 50 mg/kg) did not produce significant antihyperglycemic action, it lowered the serum MCP-1 levels significantly in alloxan-induced diabetic mice. Therefore, our results suggest that scutellarin has anti-inflammation effect that may afford some protection against hyperglycemia-induced vascular inflammatory both in vitro and in vivo.
At some point in our life, we realize that we need to pause, pay attention to our mind, body, and soul. The constant things that we encounter every day might take away our focus in taking care of ourselves. It is then we realize we need to take a shift from our current life's situation.Today's guest, Alma Omeralovic, whose passion is connecting with people, worked in corporate for 50+ hours a week and believe she had her life under control, shares her experience how she transitioned out of corporate America into being a Yogi and meditation leader.
Alma was having a number of panic attacks per day that led her to the hospital. Even the little things she experiences daily was causing too much stress and anxiety. It was until she got a package for one month of yoga and went to try it out. After her session, she felt amazing and thought she needed to learn more about the practice. Discovering the great things that this practice have brought to her, she decided to be more involved and went to a yoga retreat and became certified as a yoga teacher herself!
Changing her focus and listening more to healing her body, Alma wanted to share her experience and journey on how she overcome these obstacles, especially suffering from panic attacks and anxiety.
IN THIS EPISODE YOU WILL:
Discover the benefits of surrounding your self with positive people
Realize the importance of listening to your intuition
Be more focus on taking care of your body
Learn about the benefit of yoga and meditation
INSIGHTS:
"Self-care should feel good if it feels like an obligation then it's something else." -Alma Omeralovic
"Don't let something that you love to do become just another check mark on the list." -Alma Omeralovic
"I love to write things down, especially writing my planner for the week!" -Alma Omeralovic
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BACKGROUND: Oxidative stress is concomitant with acetaminophen (APAP)-induced hepatotoxicity, which has been highlighted as therapeutic targets for such diseases. The berries of Seabuckthorn (Hippophae rhamnoides L.) have been traditionally used in Tibetan medicine for thousands of years. The effect of Seabuckthorn berry polysaccharide on drug- induced liver injury (DILI) has not yet been elucidated.PURPOSE: This study aims to investigate the protective effects and mechanisms of Seabuckthorn polysaccharide (SP) against APAP-induced hepatotoxicity.
STUDY DESIGN: Sixty C57BL/6 mice were randomly divided into six groups (n = 10 per group), namely the control group (Ctrl), APAP-induced-liver injury group (APAP), NAC pretreated group (NAC), 100 mg/kg SP pretreated group (APAP/SP100), 200 mg/kg SP pretreated group (APAP/SP200) and 200 mg/kg SP pretreated group without APAP challenge (SP200). SP was given orally to mice for 30 consecutive days prior to APAP exposure (300 mg/kg). NAC (150 mg/kg) was administrated 1 h before APAP challenge.
METHODS: ALT and AST were detected 16 h after APAP treatment; Hepatic expression of GSH, SOD, NO, iNOS and GSH-Px were examined. The expression of p-JNK, Bcl-2/Bax, p62, Keap-1 and SOD-2 was detected by Western blotting. The expression of Nrf-2 and its target genes HO-1, GCLC and NQO-1 were analyzed by RT-PCR and Western blotting.
RESULTS: Pretreatment with SP led to decreased levels of ALT and AST in APAP mice, without affecting APAP metabolism. This was accompanied by diminished liver injuries, increased levels of GSH and GSH-Px, reduced NO and iNOS expression. SP increased the activity of SOD as well as SOD-2 expression in APAP mice. SP suppressed APAP-induced JNK phosphorylation and increased the ratio of Bcl-2/Bax. Furthermore, SP decreased the expression of Keap-1 and increased the nuclear expression of Nrf-2. The expression of Nrf-2 target gene HO-1 was increased by SP pretreatment in APAP mice.
CONCLUSION: SP alleviates APAP-induced hepatotoxicity. The protective effects of SP are associated with the activation of the Nrf-2/HO-1-SOD-2 signaling pathway.
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