Mindfulness-based cognitive therapy (MBCT) has been demonstrated to be successful in the prevention of relapse in patients with recurrent major depressive disorder (MDD). With regard to its working mechanisms, it is hypothesized that mindfulness meditation influences the processing of emotional information and that it could therefore reduce cognitive vulnerability factors that are observed during and after remission of depressive episodes. In this study we investigated the effects of an 8 week MBCT training versus no intervention on the facilitation and inhibition of attention for sad versus happy faces in a group of people with a history of MDD, N = 45. The comparison group consisted of a non-treatment seeking group with a history of MDD, recruited from the community, N = 26. At baseline, we found that formerly depressed patients who applied for MBCT training inhibited attention for positive information, and showed facilitation of attention for negative information. However, the comparison group did not show similar attentional characteristics. After MBCT, participants showed a reduced facilitation of attention for negative information and a reduced inhibition of attention for positive information, which is indicative of open attention towards all emotional information.
Compared to the general population, youth in foster care experience multiple psychosocial difficulties due to exceptionally high rates of maltreatment. Many youth in care receive psychological and/or psychotropic treatment but not all require or are willing to accept that level of intervention. For many, a “mental health” approach feels pathologizing. Nevertheless, these youth have suffered maltreatment and interventions to improve their ability to cope with past trauma and their often uncertain present are clearly needed. Cognitively-Based Compassion Training (CBCT) provides an alternative perspective on suffering and can be framed as a wellness intervention that is appropriate for all humans. The present study examined whether a 6-week CBCT intervention would improve psychosocial functioning among adolescents in foster care. Seventy adolescents were randomized to CBCT (twice weekly) or a wait-list condition. Youth were assessed at baseline and after 6 weeks. Groups did not differ on measures of psychosocial functioning following training; however practice frequency was associated with increased hopefulness and a trend for a decrease in generalized anxiety. Qualitative results indicated that participants found CBCT useful for dealing with daily life stressors. Adolescents in care were willing to engage in CBCT. The majority reported CBCT was very helpful and almost all reported they would recommend CBCT to a friend. Participants reported specific instances of using CBCT strategies to regulate emotion, manage stress, or to respond more compassionately towards others. Standardized self-report measures were not sensitive to qualitative reports of improved functioning, suggesting the need for measures more sensitive to the positive changes noted or longer training periods to demonstrate effects. Practical issues surrounding implementation of such programs in high-risk youth populations are identified. Recommendations are provided for further development.
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Compared to the general population, youth in foster care experience multiple psychosocial difficulties due to exceptionally high rates of maltreatment. Many youth in care receive psychological and/or psychotropic treatment but not all require or are willing to accept that level of intervention. For many, a “mental health” approach feels pathologizing. Nevertheless, these youth have suffered maltreatment and interventions to improve their ability to cope with past trauma and their often uncertain present are clearly needed. Cognitively-Based Compassion Training (CBCT) provides an alternative perspective on suffering and can be framed as a wellness intervention that is appropriate for all humans. The present study examined whether a 6-week CBCT intervention would improve psychosocial functioning among adolescents in foster care. Seventy adolescents were randomized to CBCT (twice weekly) or a wait-list condition. Youth were assessed at baseline and after 6 weeks. Groups did not differ on measures of psychosocial functioning following training; however practice frequency was associated with increased hopefulness and a trend for a decrease in generalized anxiety. Qualitative results indicated that participants found CBCT useful for dealing with daily life stressors. Adolescents in care were willing to engage in CBCT. The majority reported CBCT was very helpful and almost all reported they would recommend CBCT to a friend. Participants reported specific instances of using CBCT strategies to regulate emotion, manage stress, or to respond more compassionately towards others. Standardized self-report measures were not sensitive to qualitative reports of improved functioning, suggesting the need for measures more sensitive to the positive changes noted or longer training periods to demonstrate effects. Practical issues surrounding implementation of such programs in high-risk youth populations are identified. Recommendations are provided for further development.
Compared to the general population, youth in foster care experience multiple psychosocial difficulties due to exceptionally high rates of maltreatment. Many youth in care receive psychological and/or psychotropic treatment but not all require or are willing to accept that level of intervention. For many, a “mental health” approach feels pathologizing. Nevertheless, these youth have suffered maltreatment and interventions to improve their ability to cope with past trauma and their often uncertain present are clearly needed. Cognitively-Based Compassion Training (CBCT) provides an alternative perspective on suffering and can be framed as a wellness intervention that is appropriate for all humans. The present study examined whether a 6-week CBCT intervention would improve psychosocial functioning among adolescents in foster care. Seventy adolescents were randomized to CBCT (twice weekly) or a wait-list condition. Youth were assessed at baseline and after 6 weeks. Groups did not differ on measures of psychosocial functioning following training; however practice frequency was associated with increased hopefulness and a trend for a decrease in generalized anxiety. Qualitative results indicated that participants found CBCT useful for dealing with daily life stressors. Adolescents in care were willing to engage in CBCT. The majority reported CBCT was very helpful and almost all reported they would recommend CBCT to a friend. Participants reported specific instances of using CBCT strategies to regulate emotion, manage stress, or to respond more compassionately towards others. Standardized self-report measures were not sensitive to qualitative reports of improved functioning, suggesting the need for measures more sensitive to the positive changes noted or longer training periods to demonstrate effects. Practical issues surrounding implementation of such programs in high-risk youth populations are identified. Recommendations are provided for further development.
BackgroundCognitive problems frequently occur in patients with multiple sclerosis (MS) and profoundly affect their quality of life. So far, the best cognitive treatment options for MS patients are a matter of debate. Therefore, this study aims to investigate the effectiveness of two promising non-pharmacological treatments: cognitive rehabilitation therapy (CRT) and mindfulness-based cognitive therapy (MBCT). Furthermore, this study aims to gain additional knowledge about the aetiology of cognitive problems among MS patients, since this may help to develop and guide effective cognitive treatments.
Methods/design
In a dual-centre, single-blind randomised controlled trial (RCT), 120 MS patients will be randomised into one of three parallel groups: CRT, MBCT or enhanced treatment as usual (ETAU). Both CRT and MBCT consist of a structured 9-week program. ETAU consists of one appointment with an MS specialist nurse. Measurements will be performed at baseline, post-intervention and 6 months after the interventions. The primary outcome measure is the level of subjective cognitive complaints. Secondary outcome measures are objective cognitive function, functional brain network measures (using magnetoencephalography), psychological symptoms, well-being, quality of life and daily life functioning.
Discussion
To our knowledge, this will be the first RCT that investigates the effect of MBCT on cognitive function among MS patients. In addition, studying the effect of CRT on cognitive function may provide direction to the contradictory evidence that is currently available. This study will also provide information on changes in functional brain networks in relation to cognitive function. To conclude, this study may help to understand and treat cognitive problems among MS patients.
This book contains the fifteen numbers of the renowned Wheel Publication series, dealing with various aspects of the Buddha’s teaching. Wheel Publication No. 16: Buddhism and Christianity — Helmuth von Glasenapp; 17: Three Cardinal Discourses of the Buddha — Nyanamoli Thera; 18: Devotion in Buddhism — Nyanaponika Thera, Acarya Buddharakkhita, & Kassapa Thera; 19: The Foundations of Mindfulness — Nyanasatta Thera; 20: The Three Signata: Anicca, Dukkha, Anatta — Dr. O. H. de A. Wijesekera; 21: The Removal of Distracting Thoughts — Soma Thera; 22: Buddha The Healer — Dr. Ananda Nimalasuria; 23: The Nature and Purpose of the Ascetic Ideal — Ronald Fussell; 24–5: Live Now — Ananda Pereira; 26: The Five Mental Hindrances and Their Conquest — Nyanaponika Thera; 27–8: Going Forth — Sumana Samanera; 29: The Light of Asia or The Great Renunciation — Edwin Arnold,; 30: Women in Early Buddhist Literature — I. B. Horner.
Complementary and integrative treatments, such as massage, acupuncture, and yoga, are used by increasing numbers of cancer patients to manage symptoms and improve their quality of life. In addition, such treatments may have other important and currently overlooked benefits by reducing tissue stiffness and improving mobility. Recent advances in cancer biology are underscoring the importance of connective tissue in the local tumor environment. Inflammation and fibrosis are well-recognized contributors to cancer, and connective tissue stiffness is emerging as a driving factor in tumor growth. Physical-based therapies have been shown to reduce connective tissue inflammation and fibrosis and thus may have direct beneficial effects on cancer spreading and metastasis. Meanwhile, there is currently little knowledge on potential risks of applying mechanical forces in the vicinity of tumors. Thus, both basic and clinical research are needed to understand the full impact of integrative oncology on cancer biology as well as whole person health. Cancer Res; 76(21); 6159-62. (c)2016 AACR.
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This paper presents a selective review of the literature addressing the influence of young children's conversational environments and interactions on their psychological understanding of persons. Our dual purposes are to reveal some consensus on the current state of knowledge and to foster a programmatic approach to future research. The initial sections clarify what is meant by conversation and describe the nature of theory-of-mind development. We adopt the term socio-cognitive development to convey the fact that children's theory-of-mind understanding becomes more elaborate and flexible throughout childhood, and we discuss issues of measurement. The following sections deal directly with the influence of conversational environments and interactions on children's socio-cognitive understanding. We present findings that suggest that conversational interactions are of fundamental importance for the development of children's socio-cognitive understanding, and we examine the particular aspects of the former that have been shown to be the most effective in promoting the latter. We discuss the relationship between children's conversational references to thoughts and feelings and experimental assessments of their socio-cognitive understanding, and we offer a detailed list of considerations for future research. In the remaining sections, we highlight the important roles of (i) young children's expanding linguistic competence and (ii) their relationships, and we discuss implications for individual differences in children's developing social competence.
This study reports physical and psychological health outcomes following mindfulness-based stress reduction (MBSR) training in an inner city environment. Results show: (a) the relative difficulty contacting referrals; (b) a relatively high completion rate (65%) eleven people have enrolled in the program; and (c) clinically and statistically significant reductions over the eight weeks of the intervention period in measures of medical symptoms (MSCL) and anxiety (BAI), and corresponding increases in self-esteem (Self-Esteem Inventory) and mental health (SF- 36). A small follow-up sample characteristic of the larger population showed maintenance of these changes for periods of up to seven years. The limitations of this uncontrolled descriptive study and the particular challenges and rewards of working in this environment are discussed.
The autism spectrum disorder (ASD) is a neurodevelopment disorder that affects areas related to social skills, such as social interaction, communication, planning everyday activities, imagination, and creativity, in a permanent way and since early ages. These skills are very important for everyday routine and should be developed to improve the life quality and integrate people with such disorders in the workplace. Nowadays, there are several applications that were developed to support children with ASD. However, most of those applications were developed in other languages or are aimed at different social contexts. Some of them are simply outdated. Due to the mentioned factors, an application for mobile devices was developed, aimed at supporting professionals that intend to develop skills related to empathy based on the mind theory, in children diagnosed with ASD. In the tests with experts, it was possible to obtain an adequate application both in terms of content and usability for them, allowing the user to feel comfortable with the application and that this can be integrated into their activities without problems. Using the usability tests, the results show that both the users managed to complete the tasks with some time differences. The application was validated by performing several tests with experts and final users with promising results.
This study examined developmental toxicity of different mercury compounds, including some used in traditional medicines. Medaka (Oryzias latipes) embryos were exposed to 0.001-10 µM concentrations of MeHg, HgCl2, α-HgS (Zhu Sha), and β-HgS (Zuotai) from stage 10 (6-7 hpf) to 10 days post fertilization (dpf). Of the forms of mercury in this study, the organic form (MeHg) proved the most toxic followed by inorganic mercury (HgCl2), both producing embryo developmental toxicity. Altered phenotypes included pericardial edema with elongated or tube heart, reduction of eye pigmentation, and failure of swim bladder inflation. Both α-HgS and β-HgS were less toxic than MeHg and HgCl2. Total RNA was extracted from survivors three days after exposure to MeHg (0.1 µM), HgCl2 (1 µM), α-HgS (10 µM), or β-HgS (10 µM) to examine toxicity-related gene expression. MeHg and HgCl2 markedly induced metallothionein (MT) and heme oxygenase-1 (Ho-1), while α-HgS and β-HgS failed to induce either gene. Chemical forms of mercury compounds proved to be a major determinant in their developmental toxicity.
PREMISE OF THE STUDY: Ephedragerardiana (Ephedraceae), occurring in the Himalayan ranges, is an important plant species used in Tibetan medicine. Due to the lack of molecular markers to characterize genetic diversity, knowledge for conservation and uses of E. gerardiana resources is limited; we therefore developed microsatellite markers for use in this species.METHODS AND RESULTS: Using Illumina MiSeq sequencing technology, we developed 29 polymorphic microsatellite loci suitable for E. gerardiana, of which 15 loci also showed polymorphisms in two related Ephedra species, E. saxatilis and E. monosperma. The average number of effective alleles per locus ranged from two to six. The observed and expected heterozygosity ranged from 0.23 to 0.83 and 0.44 to 0.86, respectively, in E. gerardiana populations.
CONCLUSIONS: The developed 29 microsatellite markers are effective for the study of genetic structure and genetic diversity of E. gerardiana, and 15 of these markers are suitable for related Ephedra species.
PREMISE OF THE STUDY: Ephedragerardiana (Ephedraceae), occurring in the Himalayan ranges, is an important plant species used in Tibetan medicine. Due to the lack of molecular markers to characterize genetic diversity, knowledge for conservation and uses of E. gerardiana resources is limited; we therefore developed microsatellite markers for use in this species. METHODS AND RESULTS: Using Illumina MiSeq sequencing technology, we developed 29 polymorphic microsatellite loci suitable for E. gerardiana, of which 15 loci also showed polymorphisms in two related Ephedra species, E. saxatilis and E. monosperma. The average number of effective alleles per locus ranged from two to six. The observed and expected heterozygosity ranged from 0.23 to 0.83 and 0.44 to 0.86, respectively, in E. gerardiana populations. CONCLUSIONS: The developed 29 microsatellite markers are effective for the study of genetic structure and genetic diversity of E. gerardiana, and 15 of these markers are suitable for related Ephedra species.
<p>This paper traces the historical development of the <em>prabhamandala</em>, the back-support consisting of a throne and triumphal arch, on which deities are depicted in paintings and sculptures. From early Indian to later Tibetan examples, the depiction of the prabhamandala underwent successive developments, incorporating different elements and changing stylisticly. (Ben Deitle 2006-05-04)</p>
BackgroundPoor social cognition is prevalent in schizophrenia spectrum disorders. Some authors argue that these effects are symptom-specific and that socio-cognitive difficulties (e.g. theory of mind) are strongly associated with thought disorder and symptoms of disorganisation.
Aims
The current review tests the strength of this association.
Method
We meta-analysed studies published between 1980 and 2016 that tested the association between social cognition and these symptoms in schizophrenia spectrum disorders.
Results
Our search (PsycINFO, MEDLINE and Web of Science) identified 123 studies (N = 9107). Overall effect size as r = −0.313, indicating a moderate association between symptoms and social cognition. Subanalyses yielded a moderate association between symptoms and theory of mind (r = −0.349) and emotion recognition (r = −0.334), but smaller effect sizes for social perception (r = −0.188), emotion regulation (r = −0.169) and attributional biases (r = −0.143).
Conclusions
The association is interpreted within models of communication that highlight the importance of mentalisation and processing of partner-specific cues in conversational alignment and grounding.
Declaration of interests
None.
This study investigated the effects of a brief mindfulness intervention on romantic partners’ physiological responses to conflict stress moderated by trait mindfulness. Young adult couples (n = 101 dyads) completed the Five Facet Mindfulness Questionnaire (FFMQ) to assess trait mindfulness approximately 1 week prior to a laboratory session involving a conflict discussion task. One third of partners were randomly assigned to a mindfulness induction condition before the conflict (remaining participants were assigned to a perspective taking or control condition). All participants gave five saliva samples over the course of the session to measure autonomic (salivary alpha-amylase, sAA) and neuroendocrine (cortisol) stress responses. There were no main effects of participation in the mindfulness condition, but analyses revealed differing intervention impacts for partners with high vs. low dispositional mindfulness. According to region of significance testing, partners with high FFMQ scores (top 23 % of men, 12 % of women) showed better stress regulation in the mindfulness condition, i.e., more dynamic sAA reactivity/recovery curves for men and quicker post-stress cortisol recovery for women, whereas those with low FFMQ scores (bottom 5 % of men, 11 % of women) showed poorer regulation, i.e., flatter sAA responses. Implications for using mindfulness to foster stress regulation are discussed.
Little is known about whether followers who perceive ethical leadership are more easily moved to act compassionately with peers. This study hypothesizes four compassionate feelings as mediators of the relationship between ethical leadership and interpersonal citizenship behavior directed at peers: (a) empathic concern or an other-oriented emotional response elicited by and congruent with the perceived welfare of a peer in need; (b) mindfulness, a state of consciousness in which attention is focused on present-moment phenomena; (c) kindness, understanding the pain or suffering of peers; and (d) common humanity, viewing peers' experiences as part of the larger human experience. Data were obtained from 300 followers working in three-member groups with a common leader in each of 100 investment banks in the city of London. Results indicated that: (a) ethical leadership was significantly and positively linked to compassion and peer-focused citizenship and (b) common humanity is the only compassionate feeling that mediates the link between ethical leadership and peer-focused citizenship. Findings suggest that supervisors who act morally more easily move their followers to become sensitized to peers' setbacks and misfortunes and take action in the form of interpersonal OCBs to lessen or relieve their suffering.
Cultivating empathy is a presumed benefit of mindfulness, but this possibility has rarely been investigated experimentally. We examined whether a five-minute mindfulness exercise would cultivate empathy relative to two equally brief control exercises: relaxation and mind-wandering. We further examined whether mindfulness would be especially beneficial for people with autistic or narcissistic traits. Results showed no effect of mindfulness relative to both control conditions on mind reading, empathic responding, or prosocial behavior. Mindfulness effects were independent of autistic traits. Unexpectedly, people higher in autistic traits did show increased prosocial behavior across conditions. Intriguingly, mindfulness improved mind reading in non-narcissistic people, but reduced it in narcissistic people. These findings question whether a brief mindfulness exercise is sufficient for building empathy.
Background: Although aesthetic correction of facial aging had long been the exclusive domain of plastic surgeons and dermatologists, alternative nonmedical approaches to facial rejuvenation are becoming more popular, such as facial acupuncture, facial acupressure, and facial exercises. However, the effectiveness of these alternative approaches is still a topic of debate. Objectives: The authors review the evidence of the effectiveness of facial exercises for facial rejuvenation. Methods: A literature search was performed in Medline, Web of Science, Science Direct, SciELO, and LILACS databases for the terms facial rejuvenation, facial exercises, facial massage, face building, face yoga, (oro)facial (a)esthetics, (a)esthetic logopedics, and (a)esthetic speech therapy. Nine reports were identified from the search and were subject to further assessment. Results: Although positive outcomes were achieved in all 9 studies, none of the studies used a control group and randomization process. They were single case reports, small case series, or studies with a single-group pretest-posttest design. Moreover, the effectiveness assessments in most of the studies were purely subjective, carried out by the authors and/or the patients themselves, without blinding. Conclusions: The evidence to date is insufficient to determine whether facial exercises are effective for facial rejuvenation. Evidence from large randomized controlled trials will be needed before conclusions can be drawn.
The effectiveness of an 8-week mindfulness training for adolescents aged 11–15 years with ADHD and parallel Mindful Parenting training for their parents was evaluated, using questionnaires as well as computerized attention tests. Adolescents (N = 10), their parents (N = 19) and tutors (N = 7) completed measurements before, immediately after, 8 weeks after and 16 weeks after training. Adolescents reported on their attention and behavioral problems and mindful awareness, and were administered two computerized sustained attention tasks. Parents as well as tutors reported on adolescents’ attention and behavioral problems and executive functioning. Parents further reported on their own parenting, parenting stress and mindful awareness. Both the mindfulness training for the adolescents and their parents was delivered in group format. First, after mindfulness training, adolescents’ attention and behavior problems reduced, while their executive functioning improved, as indicated by self-report measures as well as by father and teacher report. Second, improvements in adolescent’ actual performance on attention tests were found after mindfulness training. Moreover, fathers, but not mothers, reported reduced parenting stress. Mothers reported reduced overreactive parenting, whereas fathers reported an increase. No effect on mindful awareness of adolescents or parents was found. Effects of mindfulness training became stronger at 8-week follow-up, but waned at 16-week follow-up. Our study adds to the emerging body of evidence indicating that mindfulness training for adolescents with ADHD (and their parents) is an effective approach, but maintenance strategies need to be developed in order for this approach to be effective in the longer term.
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Studies on the effects of mindfulness interventions on mental health and behavioral problems in children show promising results, but are primarily conducted with selected samples of children. The few studies investigating school-based interventions used self-selected samples, provided training outside of the classroom, and did not report longer-term effects. The immediate and longer-term effects of a class-based mindfulness intervention for elementary school children were investigated as a primary prevention program (MindfulKids) to reduce stress and stress-related mental health and behavioral problems. Children (8–12 years) from three elementary schools participated. Classes were randomized to an immediate-intervention group (N = 95) or a waitlist-control group (N = 104), which received the intervention after a waitlist period. Twelve 30-min sessions were delivered in 6 weeks. At baseline, pretest, posttest, and follow-up, variables indicative of stress and metal well-being were assessed with children, variables indicative of mental health problems were assessed with parents, and teachers reported on class climate. Multilevel analysis revealed that there were no significant changes from baseline to pretest. Some primary prevention effects on stress and well-being were found directly after training and some became more apparent at follow-up. Effects on mental health problems also became apparent at follow-up. MindfulKids seems to have a primary preventive effect on stress, well-being, and behavior in schoolchildren, as reported by children and parents. Exploratory analysis revealed that children who ruminate more are affected differently by the intervention than children who ruminate less. It is concluded that mindfulness training can be incorporated in elementary schools at the class level, letting all children benefit from the intervention.
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Studies on the effects of mindfulness interventions on mental health and behavioral problems in children show promising results, but are primarily conducted with selected samples of children. The few studies investigating school-based interventions used self-selected samples, provided training outside of the classroom, and did not report longer-term effects. The immediate and longer-term effects of a class-based mindfulness intervention for elementary school children were investigated as a primary prevention program (MindfulKids) to reduce stress and stress-related mental health and behavioral problems. Children (8–12 years) from three elementary schools participated. Classes were randomized to an immediate-intervention group (N = 95) or a waitlist-control group (N = 104), which received the intervention after a waitlist period. Twelve 30-min sessions were delivered in 6 weeks. At baseline, pretest, posttest, and follow-up, variables indicative of stress and metal well-being were assessed with children, variables indicative of mental health problems were assessed with parents, and teachers reported on class climate. Multilevel analysis revealed that there were no significant changes from baseline to pretest. Some primary prevention effects on stress and well-being were found directly after training and some became more apparent at follow-up. Effects on mental health problems also became apparent at follow-up. MindfulKids seems to have a primary preventive effect on stress, well-being, and behavior in schoolchildren, as reported by children and parents. Exploratory analysis revealed that children who ruminate more are affected differently by the intervention than children who ruminate less. It is concluded that mindfulness training can be incorporated in elementary schools at the class level, letting all children benefit from the intervention.
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