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The purpose of the present study was to examine whether mindfulness predicts general trust and social support among trauma-exposed college students, as well as to examine the potential moderating effect of posttraumatic stress on these relationships. Participants consisted of 536 trauma-exposed college students attending a public university in the southeast United States. After controlling for PTSD symptoms and type of trauma, mindfulness was positively associated with general trust and social support at low and mean levels of PTSD symptomatology; however, the relationships between mindfulness and these variables were nonsignificant at high levels of PTSD symptomatology.