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Purpose. To examine the effects of a Tai Chi Chung (TCC) program, an efficiency approach, on anxiety and cardiovascular risk factors. Cardiovascular diseases (CVDs) reDesign. A quasi-experimental study. main the leading cause of morbidity Setting. A community in Taipei City, Taixuan. and mortality worldwide and constitute Subjects. One hundred thirty-three adults aged 55 years and older. a major problem to medical science and Intervention. Sixty-four participants (experimental group) attended a 60-minute Tai Chi exercise three public health.' In Taiwan, heart disease times per lueekfor 12 weeks, whereas 69 participants (control group) maintained their usual daily activities. and CVD are the second and third Measures. Anxiety states, systolic blood pressure (SBP), diastolic blood pressure (DBP), body mass leading causes of death, respectively.^ index (BMI), and waist circumference (WC) were assessed at baseline, 6 weeks into the experiment, and 12 weeks into tlie experiment. Analysis. Generalized estimjiting equations were used to evaluate the changes.Results. Participants showed a greater drop in anxiety levels (ß = -2.57, p= .001) and DBP (ß = -7.02, p < .001) at the 12-week follow-up than did the controls. SBP significantly decreased in the 6-week follow-up and 12-week folloxo-up tests. The participants in the intervention achieved a greater drop in BMJ at the 6-week and 12-zueek follow-up visits than the controls. The interventions demonstrated decreased average WC at the 6-week and 12-week folhw-up visits as compared to tlie controls.
Conclusion. The results highlight the long-term benefits of a TCC program in facilitating health promotion by reducing anxiety and risk factors for cardiovascular diseases. (Am f Health Promot 201328[l]:16-22.)
Because of the morphological and macroscopic similarity, many species of Erigeron and Aster (Asteraceae) are confusable and usually used under the same name "Meiduoluomi" in traditional Tibetan medicine (TTM). To find an easy, quick, and reliable method to authenticate and distinguish the eight main medicinal plants of these species, the light microscope was used to reveal the morphoanatomic details. The fixed, sectioned, and stained plant materials and epidermis materials were studied by microscopic techniques. The results of the microscopic features are systematically described and illustrated, and comparison parameters are presented. Furthermore, a key to the eight species of "Meiduoluomi" was constructed. Microscopy can be unambiguously used to authenticate and distinguish the eight main species of TTM "Meiduoluomi.";
Because of the morphological and macroscopic similarity, many species of <i>Erigeron</i> and <i>Aster</i> (Asteraceae) are confusable and usually used under the same name “Meiduoluomi” in traditional Tibetan medicine (TTM). To find an easy, quick, and reliable method to authenticate and distinguish the eight main medicinal plants of these species, the light microscope was used to reveal the morphoanatomic details. The fixed, sectioned, and stained plant materials and epidermis materials were studied by microscopic techniques. The results of the microscopic features are systematically described and illustrated, and comparison parameters are presented. Furthermore, a key to the eight species of “Meiduoluomi” was constructed. Microscopy can be unambiguously used to authenticate and distinguish the eight main species of TTM “Meiduoluomi.” Microsc. Res. Tech., 2009. © 2009 Wiley-Liss, Inc.
This paper evaluates the benefits of meditation in regard to emotional intelligence (EI), perceived stress and negative mental health with cross-sectional and experimental studies. It first studied 351 full-time working adults with different amounts of experience in meditation for these factors in order to test the hypothesis that their differences in them were based on differences in meditation experience, and found that those participants with greater meditation experience exhibited higher EI, and less perceived stress and negative mental health than those who had less or none. It then randomly divided 20 graduate students with no previous experience of meditation into a mindfulness meditation group (n = 10) and a control group (n = 10), and measured them for the same variable pre-treatment and post-treatment to test the hypothesis that meditation training improves people's state, and found that those who completed the mindfulness meditation training demonstrated significant improvements compared to the control group.
An alarming number of students drop out of junior high school in developing countries. In this study, we examine the impacts of providing a social-emotional learning (SEL) program on the dropout behavior and learning anxiety of students in the first two years of junior high. We do so by analyzing data from a randomized controlled trial involving 70 junior high schools and 7,495 students in rural China. After eight months, the SEL program reduces dropout by 1.6 percentage points and decreases learning anxiety by 2.3 percentage points. Effects are no longer statistically different from zero after 15 months, perhaps due to decreasing student interest in the program. However, we do find that the program reduces dropout among students at high risk of dropping out (older students and students with friends who have already dropped out), both after eight and 15 months of exposure to the SEL program.
Zuotai, a famous Tibetan medicinal mixture containing β-HgS, has been used to combine with herbal remedies for treating diseases for more than 1 300 years. The target organ for inorganic mercury toxicity is generally considered to be the kidney. Therefore, it is crucial to reveal the chemical speciation, spatial distribution and potential nephrotoxicity of mercury from Zuotai in kidney. To date, this remains poorly understood. We used X-ray absorption spectroscopy (XAS) and micro X-ray fluorescence (μ-XRF) imaging based on synchrotron radiation to study mercury chemical forms and mercury special distribution in kidney after mice were treated orally with Zuotai, β-HgS or HgCl2. Meanwhile, the histopathology of kidney was observed. Mice exposed with Zuotai showed kidney with significant proportion of mercury ions bound to sulfydryl biomolecules (e.g. Cys-S-Hg-S-Cys) plus some of unknown species, but without methylmercury cysteine, which is the same as β-HgS and HgCl2. The mercury is mainly deposited in renal cortex in mouse treated with Zuotai, β-HgS or HgCl2, but with a low level of mercury in medulla. The total mercury in kidney of mice treated with HgCl2 was much higher than that of β-HgS, and the later was higher than that of Zuotai. And, HgCl2 cause severe impairments in mouse kidney, but that was not observed in the Zuotai and β-HgS groups. Meanwhile, the bio-metals (Ca, Zn, Fe and Cu) micro-distributions in kidney were also revealed. These findings elucidated the chemical nature, spatial distribution and toxicity difference of mercury from Zuotai, β-HgS and HgCl2 in mouse kidney, and provide new insights into the appropriate methods for biological monitoring.
The flower buds of five <i>Lonicera</i> species, <i>Lonicera japonica</i> Thunb., <i>L. macranthoides</i> Hand.-Mazz., <i>L. hypoglauca</i> Miq., <i>L. confusa</i> DC. and <i>L. fulvotomentosa</i> Hsu et S.C. Cheng are confusable and usually utilized under the same name “Jinyinhua” in different areas for morphological similarity. Studies found that these five species possess extreme differences in chemical compounds, correspondingly showing different pharmacological activities and clinical applications. To ensure efficacy and safety of these herbal medicines and prevent unknown adverse effect, in this work, a simple, rapid and effective method combining normal light and fluorescence microscopy was developed for authentication. Surface slides and transverse sections of these buds were investigated to reveal their differences. As a routine technique, normal light microscopy which gives detailed microscopic features such as glandular hairs and nonglandular hairs, can easily distinguish four species except <i>L. confusa</i>. Fluorescence technique, which could present different distribution of fluorescence materials, is further employed to identify three species including <i>L. confusa</i> successfully. It is the first report to identify these five <i>Lonicera</i> species by combining normal light and fluorescence microscopy. This work indicated combining normal light and fluorescence microscopy could be a powerful method in authentication of confused species. Microsc. Res. Tech.74:133-141, 2011. © 2010 Wiley-Liss, Inc.
BACKGROUND: Yoga, a popular mind-body practice, may produce changes in cardiovascular disease (CVD) and metabolic syndrome risk factors. DESIGN: This was a systematic review and random-effects meta-analysis of randomized controlled trials (RCTs). METHODS: Electronic searches of MEDLINE, EMBASE, CINAHL, PsycINFO, and The Cochrane Central Register of Controlled Trials were performed for systematic reviews and RCTs through December 2013. Studies were included if they were English, peer-reviewed, focused on asana-based yoga in adults, and reported relevant outcomes. Two reviewers independently selected articles and assessed quality using Cochrane's Risk of Bias tool. RESULTS: Out of 1404 records, 37 RCTs were included in the systematic review and 32 in the meta-analysis. Compared to non-exercise controls, yoga showed significant improvement for body mass index (-0.77 kg/m(2) (95% confidence interval -1.09 to -0.44)), systolic blood pressure (-5.21 mmHg (-8.01 to -2.42)), low-density lipoprotein cholesterol (-12.14 mg/dl (-21.80 to -2.48)), and high-density lipoprotein cholesterol (3.20 mg/dl (1.86 to 4.54)). Significant changes were seen in body weight (-2.32 kg (-4.33 to -0.37)), diastolic blood pressure (-4.98 mmHg (-7.17 to -2.80)), total cholesterol (-18.48 mg/dl (-29.16 to -7.80)), triglycerides (-25.89 mg/dl (-36.19 to -15.60), and heart rate (-5.27 beats/min (-9.55 to -1.00)), but not fasting blood glucose (-5.91 mg/dl (-16.32 to 4.50)) nor glycosylated hemoglobin (-0.06% Hb (-0.24 to 0.11)). No significant difference was found between yoga and exercise. One study found an impact on smoking abstinence. CONCLUSIONS: There is promising evidence of yoga on improving cardio-metabolic health. Findings are limited by small trial sample sizes, heterogeneity, and moderate quality of RCTs.
The objective of this study was to examine how and to what extent a new degradable polymeric fiber, poly(p‐dioxanone), used as a surgical suture material, degrades in the presence of enzymes and after γ‐irradiation. The degradation of the fiber was studied mechanically using an Instron and morphologically by SEM. Both esterase and trypsin enzymes and their corresponding buffer controls were used. The fibers were γ‐irradiated at the dosages ranging from 0 to 20 Mrad, immersed in the solution for up to 70 days, and then removed for tensile strength and morphological examinations. It was found that γ‐irradiation alone lowered the tensile strength of PDS fibers and made them more susceptible to hydrolysis. Esterase and trypsin did not accelerate the hydrolytic degradtion of this fiber to any significant level. Both γ‐irradiation and enzymes influenced the gross morphological characteristic of PDS fibers when they were subjected to hydrolysis. The most important morphological observations were the formation of surface cracks and chips on the fibers and the subsequent peeling of the chips. Enzyme‐treated PDS fibers exhibited similar morphological findings but the size of the chips was smaller. The morphological observations of PDS fibers were consistent with the tensile strength data.
The article discusses hypoxic pathophysiology and high-altitude medicine as of December 2012, with a focus on the therapeutic effects of traditional Tibetan medicine Ratanasampil (RNSP) on β-amyloid (Aβ) pathologies and its potential role in Alzheimer's disease (AD) treatments. Topics include Aβ peptide production and its connection to chronic hypoxia, the use of AD transgenic mouse models, and C-terminal fragment (CTF) densitometry. Additional information is presented on the tumor necrosis factor (TNF).
OBJECTIVE: To examine the effects of an 8-week yoga program on heart rate variability and mood in generally healthy women. DESIGN: Randomized controlled trial. PARTICIPANTS: Fifty-two healthy women were randomly assigned to a yoga group or a control group. INTERVENTIONS: Participants in the yoga group completed an 8-week yoga program, which comprised a 60-minute session twice a week. Each session consisted of breathing exercises, yoga pose practice, and supine meditation/relaxation. The control group was instructed not to engage in any yoga practice and to maintain their usual level of physical activity during the study. OUTCOME MEASURES: Participants' heart rate variability, perceived stress, depressive symptoms, and state and trait anxiety were assessed at baseline (week 0) and after the intervention (week 9). RESULTS: No measures of heart rate variability changed significantly in either the yoga or control group after intervention. State anxiety was reduced significantly in the yoga group but not in the control group. No significant changes were noted in perceived stress, depression, or trait anxiety in either group. CONCLUSIONS: An 8-week yoga program was not sufficient to improve heart rate variability. However, such a program appears to be effective in reducing state anxiety in generally healthy women. Future research should involve longer periods of yoga training, include heart rate variability measures both at rest and during yoga practice, and enroll women with higher levels of stress and trait anxiety.
Before discussing Qi Gong and Tai Chi, one needs to understand clearly the concept of Qi in Chinese culture. Qi in Chinese means ‘‘air,’’ ‘‘puff,’’ or ‘‘power.’’ Qi is the universal life force that exists in all living things. No comparable word in English exists to describe Qi. In Japanese, it is called Ki, as in Reiki. In Sanskrit, it is called Prana. Qi can be compared with the electrical charge in a battery. A new battery has a full electrical charge, which can be used to operate a radio, boom box, or electric toy. When the battery is old, exhausted of all electrical charge, it no longer can be used for any battery-powered item. When a person is full of Qi, he or she can work or be active without fatigue. When the body is low in Qi, it becomes tired easily. A person with chronic fatigue syndrome can be said to be chronically low in Qi. When a person’s body is exhausted of Qi, the person is dead. At the time of birth, an infant inherits Qi from his or her parents. This Qi is called preheaven Qi, or original Qi (Yuan Qi). When the infant grows up, it requires foods to produce energy. The Qi that comes from foods is called food Qi (Gu Qi). The Gu Qi ascends up to the lung and is associated with air to become gathering Qi (Zhong Qi). The Zhong Qi is transformed to true Qi (Zhen Qi), which spreads out over the body to nourish each organ and channel. True Qi or Zhen Qi assumes two different forms: nutritive Qi (Ying Qi) and defense Qi (Wei Qi) [1]. Qi Gong and Tai Chi are special exercises designed to increase Qi in the body.
Aporphine alkaloids from the leaves of Nelumbo nucifera Gaertn are substances of great interest because of their important pharmacological activities, particularly anti-diabetic, anti-obesity, anti-hyperlipidemic, anti-oxidant, and anti-HIV's activities. In order to produce large amounts of pure alkaloid for research purposes, a novel method using high-speed counter-current chromatography (HSCCC) was developed. Without any initial cleanup steps, four main aporphine alkaloids, including 2-hydroxy-1-methoxyaporphine, pronuciferine, nuciferine and roemerine were successfully purified from the crude extract by HSCCC in one step. The separation was performed with a simple two-phase solvent system composed of n-hexane-ethyl acetate-methanol-acetonitrile-water (5:3:3:2.5:5, v/v/v/v/v). In each operation, 100 mg crude extracts was separated and yielded 6.3 mg of 2-hydroxy-1-methoxyaporphine (95.1% purity), 1.1 mg of pronuciferine (96.8% purity), 8.5 mg of nuciferine (98.9% purity), and 2.7 mg of roemerine (97.4%) respectively. The chemical structure of four aporphine alkaloids are identified by means of electrospray ionization MS (ESI-MS) and nuclear magnetic resonance (NMR) analysis. Moreover, the effects of four separated aporphine alkaloids on insulin-stimulated glucose consumption were examined in 3T3-L1 adipocytes. The results showed that 2-hydroxy-1-methoxyaporphine and pronuciferine increased the glucose consumption significantly as rosiglitazone did.
Aporphine alkaloids from the leaves of Nelumbo nucifera Gaertn are substances of great interest because of their important pharmacological activities, particularly anti-diabetic, anti-obesity, anti-hyperlipidemic, anti-oxidant, and anti-HIV's activities. In order to produce large amounts of pure alkaloid for research purposes, a novel method using high-speed counter-current chromatography (HSCCC) was developed. Without any initial cleanup steps, four main aporphine alkaloids, including 2-hydroxy-1-methoxyaporphine, pronuciferine, nuciferine and roemerine were successfully purified from the crude extract by HSCCC in one step. The separation was performed with a simple two-phase solvent system composed of n-hexane-ethyl acetate-methanol-acetonitrile-water (5:3:3:2.5:5, v/v/v/v/v). In each operation, 100 mg crude extracts was separated and yielded 6.3 mg of 2-hydroxy-1-methoxyaporphine (95.1% purity), 1.1 mg of pronuciferine (96.8% purity), 8.5 mg of nuciferine (98.9% purity), and 2.7 mg of roemerine (97.4%) respectively. The chemical structure of four aporphine alkaloids are identified by means of electrospray ionization MS (ESI-MS) and nuclear magnetic resonance (NMR) analysis. Moreover, the effects of four separated aporphine alkaloids on insulin-stimulated glucose consumption were examined in 3T3-L1 adipocytes. The results showed that 2-hydroxy-1-methoxyaporphine and pronuciferine increased the glucose consumption significantly as rosiglitazone did.
Oxidative stress is one of the major mechanisms implicated in endotoxin-induced acute lung injury. Seabuckthorn paste (SP), a traditional Tibetan medicine with high content of polyphenols and remarkable antioxidant activity, is commonly used in treating pulmonary diseases. In the present study, the protective effects and possible underlying mechanisms of SP on lipopolysaccharide- (LPS-) induced acute lung injury in mice were investigated. It was found that body weight loss, lung tissue microstructure lesions, transvascular leakage increase, malondialdehyde augmentation, and the reduction of superoxide dismutase and glutathione peroxidase levels caused by LPS challenge were all consistently relieved by SP treatment in a dose-dependent manner. Moreover, accumulation of nuclear factor erythroid 2-related factor 2 (Nrf2) in lung nuclei caused by SP treatment was observed. Our study demonstrated that SP can provide significant protection against LPS-induced acute lung injury through maintaining redox homeostasis, and its mechanism involves Nrf2 nuclear translocation and activation.
We examined self-esteem as a mediator of the relationship between mindfulness and social anxiety in a Chinese cultural context. Participants comprised 508 Chinese undergraduate students, who completed the Mindful Attention Awareness Scale, Rosenberg Self-Esteem Scale, and Interaction Anxiousness Scale. Results showed that social anxiety was negatively correlated with mindfulness and self-esteem, and that mindfulness was positively correlated with self-esteem. Mediation analysis revealed that self-esteem partially mediated the association between mindfulness and social anxiety. Thus, we suggest that mindfulness decreases social anxiety because high mindfulness fosters high self-esteem. Mindfulness practice, for example, meditation, can be used as a preventive therapy to help Chinese adults to reduce their social anxiety, and can also enhance the self-esteem of socially anxious Chinese adults.