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OBJECTIVES: The purpose of this study was to examine the effects of a structured, 8-week, Mindfulness-Based Stress Reduction (MBSR) program on perceived stress, mood, endocrine function, immunity, and functional health outcomes in individuals infected with the human immunodeficiency virus (HIV).DESIGN: This study used a quasiexperimental, nonrandomized design. METHODS: Subjects were specifically recruited (nonrandom) for intervention (MBSR) or comparison group. Data were collected at pretest and post-test in the MBSR group and at matched times in the comparison group. t Tests where performed to determine within-group changes and between-group differences. RESULTS: Natural killer cell activity and number increased significantly in the MBSR group compared to the comparison group. No significant changes or differences were found for psychological, endocrine, or functional health variables. CONCLUSIONS: These results provide tentative evidence that MBSR may assist in improving immunity in individuals infected with HIV.

OBJECTIVES: The purpose of this study was to examine the effects of a structured, 8-week, Mindfulness-Based Stress Reduction (MBSR) program on perceived stress, mood, endocrine function, immunity, and functional health outcomes in individuals infected with the human immunodeficiency virus (HIV).DESIGN: This study used a quasiexperimental, nonrandomized design. METHODS: Subjects were specifically recruited (nonrandom) for intervention (MBSR) or comparison group. Data were collected at pretest and post-test in the MBSR group and at matched times in the comparison group. t Tests where performed to determine within-group changes and between-group differences. RESULTS: Natural killer cell activity and number increased significantly in the MBSR group compared to the comparison group. No significant changes or differences were found for psychological, endocrine, or functional health variables. CONCLUSIONS: These results provide tentative evidence that MBSR may assist in improving immunity in individuals infected with HIV.

<p>A non-random study looking at the effects of a six week mindfulness-based stress reduction (MBSR) program on immunity, the endocrine system, stress, mood, and functional health of individuals with HIV. Natural killer cell activity increased significantly in the MBSR group, while there was no such gain in a comparison group. No significant effects on endocrine, psychological, or health function variables in the MBSR group. The results indicate that MBSR may strengthen the immune system of individuals with HIV, though the authors note that this is a non-randomized study with a small number of participants. (Zach Rowinski 2005-03-03)</p>