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[Obbectives] To research the fingerprints of chemical components of chloroform parts of Renqing Mangue and Renqing Mangue powder (compatibility without Zuota), and to identify Renqing Mangjue compatibility with Zuota or not. [Methods] High-performance liquid chromatography was adopted. Chromatographic column was DIKMA diamonsil (4 . 6 mm X 250 mm, 5 p.m) ; flow rate was 1 mlLmin ; column temperature was 30 ° ; mobile phase was methanol-water with gradient elution. [Results] A total of 18 common fingerprint peaks were obtained. As for the petroleum ether parts of Renqing Mangue and Renqing Mague powder (compatibility without Zuota), eiggt characteristic peas were obtained. [Conclusions] Characteristic fingerprints of chloroform parts of Renqing Mangue and Renqing Mangue powder (compatibility without Zuota) could be obtained by the high-performance liquid chromatography. Therefore, the Renqing Mangue and Renqing Mague powder (compatibility without Zuota) could be identified according to their characteristic peaks.