Displaying 1 - 3 of 3
Objectives: This study aimed to show the effectiveness of mindfulness and self-compassion therapy in improving coping abilityand adaptation to stressful situations in the elderly.
Methods: Forty-five elderly non-institutionalized adults were randomized to either treatment or a treatment waiting list. A preand post-treatment assessment was performed, consisting of the
Brief Resilient Coping Scale (BRCS), Depression Anxiety Stress
Scales (DASS), and Coping Strategies Questionnaire. The program
was developed over 10 sessions lasting 120 minutes each.
Results: Analysis of variance for repeated measures showed significant differences in the time-group interaction for the treatment’s effectiveness in improving resilience, positive reappraisal
and avoidance strategies, and decreasing anxiety, problem-solving
coping, negative self-focus, overt emotional expression and
religion.
Conclusions: The mindfulness and self-compassion program is
useful for improving resilience and coping strategies and reducing
anxiety and stress levels in the elderly.
Stroke is a severe clinical manifestation of sickle cell anemia (SCA). Despite the prognostic relevance of transcranial Doppler (TCD), more accurate tools to assess stroke risk in children with SCA are required. Here, we describe the effect of clinical, laboratory, and molecular features on the risk of stroke and high-risk TCD in children from the newborn cohort of Minas Gerais, Brazil. Outcomes studied were acute cerebral ischemia and high-risk TCD. Clinical and hematological data were retrieved from children’s records. Genetic markers, which were known for their association with stroke risk, were genotyped by polymerase chain reaction/restriction fragment length polymorphism and sequencing. The cumulative incidence of acute cerebral ischemia by the age of 8 years was 7.4 % and that of high-risk TCD by the age of 11.5 years was 14.2 %. The final multivariate model for acute cerebral ischemia risk included high white blood cell count and reticulocyte count, acute chest syndrome rate, and the single nucleotide polymorphisms (SNPs) TEK rs489347 and TNF-α rs1800629. The model for high-risk TCD included high reticulocyte count and the SNPs TEK rs489347 and TGFBR3 rs284875. Children with risk factors should be considered for intensive risk monitoring and for intervention therapy.