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Twenty Type 2 diabetic subjects between theage group of 30-60 years were studied to see the effect of 40 days of <i style="">Yoga</i> <i style="">asanas</i> on biochemical profile. The duration of diabetes ranged from 0 to 10 years. Subjects suffering from cardiac, renal and proliferative retinal complications were excluded from the study. <i style="">Yoga</i> <i style="">asanas</i> included <i style="">Surya Namaskar</i>, <i style="">Tadasan</i>, <i style="">Konasan</i>, <i style="">Padmasan</i>, <i style="">Pranayama</i>, <i style="">Paschimottanasan</i>, <i style="">Ardhmatsyendrasan</i>, <i style="">Shavasan</i>, <i style="">Pavanmuktasan</i>, <i style="">Sarpasan</i> and <i style="">Shavasan</i>. Subjects were called to the cardio-respiratory laboratory in the morning time and were given training by the <i style="">Yoga</i> expert. The <i style="">Yogic</i> exercises were performed for 30 - 40 minutes every day for 40 days in the above sequence. The subjects were prescribed medicines and diet. The basal blood glucose, lipid profile and glycosylated haemoglobin was measured and repeated after 40 days of <i style="">yoga asanas</i>. There was a statistically significant decrease in fasting blood glucose (from baseline 208.3 ± 20.0 to 171.7 ± 19.5 mg/dl) and decrease in Postprandial blood glucose (from 295.3 ± 22.0 to 269.7± 19.9 mg/dl). The decreases in values of serum cholesterol were also statistically significant (from 222.8 ± 10.2 to 207.9 ± 8.6 mg/dl). The triglyceride decreased (from 168.5 ± 15.5 to 146.3 ±13.5 mg/dl), low-density lipoprotein cholesterol and very low-density lipoprotein improved (from 144.8 ± 8.6 to 140.70 ± 7.9 mg/dl and from 37.4 ± 4.6 to 32.1 ± 3.4 mg/dl). The glycosylated haemoglobin decreased from 10.27 ±0.5 to 8.68 ± 0.4 %. These findings suggest that <i style="">yoga asanas</i> have a beneficial effect on glycaemic control and lipid profile in mild to moderate Type 2 diabetes.

OBJECTIVES: To measure the effect of the right and left nostril yoga breathing on frontal hemodynamic responses in 32 right handed healthy male subjects within the age range of 18-35 years (23.75 +/- 4.14 years). MATERIALS AND METHODS: Each subject practiced right nostril yoga breathing (RNYB), left nostril yoga breathing (LNYB) or breath awareness (BA) (as control) for 10 min at the same time of the day for three consecutive days, respectively. The sequence of intervention was assigned randomly. The frontal hemodynamic response in terms of changes in the oxygenated hemoglobin (oxyHb), deoxygenated hemoglobin (deoxyHb), and total hemoglobin (totalHb or blood volume) concentration was tapped for 5 min before (pre) and 10 min during the breathing practices using a 16 channel functional near-infrared system (FNIR100-ACK-W, BIOPAC Systems, Inc., U.S.A.). Average of the eight channels on each side (right and left frontals) was obtained for the two sessions (pre and during). Data was analyzed using SPSS version 10.0 through paired and independent samples t-test. RESULTS: Within group comparison showed that during RNYB, oxyHb levels increased significantly in the left prefrontal cortex (PFC) as compared to the baseline (P = 0.026). LNYB showed a trend towards significance for reduction in oxyHb in the right hemisphere (P = 0.057). Whereas BA caused significant reduction in deoxyHb (P = 0.023) in the left hemisphere. Between groups comparison revealed that oxyHb and blood volume in the left PFC increased significantly during RNYB as compared to BA (oxyHb: P =0.012; TotalHb: P =0.017) and LNYB (oxyHb: P =0.024; totalHb: P =0.034). CONCLUSION: RNYB increased oxygenation and blood volume in the left PFC as compared to BA and LNYB. This supports the relationship between nasal cycle and ultradian rhythm of cerebral dominance and suggests a possible application of uninostril yoga breathing in the management of psychopathological states which show lateralized cerebral dysfunctions.

OBJECTIVES: 1. To study the effect of forty days of Yogic exercises on cardiac functions in Type 2 Diabetics. 2. To study the effect of forty days of Yogic exercises on blood glucose level, glycosylated hemoglobin. METHODS: The present study done in twenty-four Type 2 DM cases provides metabolic and clinical evidence of improvement in glycaemic control and autonomic functions. These middle-aged subjects were type II diabetics on antihyperglycaemic and dietary regimen. Their baseline fasting and postprandial blood glucose and glycosylated Hb were monitored along with autonomic function studies. The expert gave these patients training in yoga asanas and they pursued those 30-40 min/day for 40 days under guidance. These asanas consisted of 13 well known postures, done in a sequence. After 40 days of yoga asanas regimen, the parameters were repeated. RESULTS: The results indicate that there was significant decrease in fasting blood glucose levels from basal 190.08 +/- 18.54 in mg/dl to 141.5 +/- 16.3 in mg/dl after yoga regimen. The post prandial blood glucose levels decreased from 276.54 +/- 20.62 in mg/dl to 201.75 +/- 21.24 in mg/dl, glycosylated hemoglobin showed a decrease from 9.03 +/- 0.29% to 7.83 +/- 0.53% after yoga regimen. The pulse rate, systolic and diastolic blood pressure decreased significantly (from 86.45 +/- 2.0 to 77.65 +/- 2.5 pulse/min, from 142.0 +/- 3.9 to 126.0 +/- 3.2 mm of Hg and from 86.7 +/- 2.5 mm of Hg to 75.5 +/- 2.1 mm of Hg after yoga regimen respectively). Corrected QT interval (QTc) decreased from 0.42 +/- 0.0 to 0.40 +/- 0.0. CONCLUSION: These findings suggest that better glycaemic control and stable autonomic functions can be obtained in Type 2 DM cases with yoga asanas and pranayama. The exact mechanism as to how these postures and controlled breathing interact with somato-neuro-endocrine mechanism affecting metabolic and autonomic functions remains to be worked out.