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Mindfulness plays an increasing role in the field of health psychology, since mindfulness-based interventions in prevention and rehabilitation can lead to a higher bodily well-being and quality of life. How valid is the measurement of self-reported mindfulness as a multidimensional construct using the German translation of the Five-Facet Mindfulness Questionnaire (FFMQ)? The 39-item inventory was translated into German and presented to a sample of 550 undergraduate students. The dimensional structure, reliability, and validity of the different scales were evaluated. Results were largely comparable to those obtained for the original English version of the FFMQ. As anticipated, the five-factor structure was largely replicated and expected associations with symptom distress and indicators of psychological and physical well-being were found. The German version of the FFMQ seems to be an economic, reliable, and valid questionnaire for assessing self-reported mindfulness in a multidimensional way.