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Khotanese remaining prescription P. 2889v was written in Khotanese.Because of the affinity between Khotan and Dunhuang, thus it appeared in the Dunhuang Library Grottoes.Traditional Indian medical work Siddhasāra copied around 982 and composed in Khotanese also unearthed in Dunhuang.It is speculated that the copy time of P. 2889v is slightly earlier than 982. The third formula prescription in P. 2889v is similar to the Kalyānaka found in the Siddhasāra and Daji Medicinal Oil Pill recorded in the Volume of Tibetan Medicine of the Chinese Medical Encyclopedia, demonstrating that this prescription had been circulating in the western region and Tibet, which indicates the spread of the Indian Ayurveda medicine in western China with profound influences.
When young refugee English language learners (ELLs) start formal schooling in the United States, the social-emotional learning (SEL) appropriate for the U.S. school context may be especially unfamiliar to them. By interviewing six elementary school teachers, this exploratory study examined how teachers describe refugee ELLs' social-emotional competencies and what pedagogical methods they report using with refugee ELLs for their social-emotional skills development. This study also considered to what extent teachers' views of their refugee ELL students' SEL and their self-reported pedagogies reflect their recognition of refugee ELLs' funds of knowledge, teachers' development of culturally sustaining pedagogies, and teachers' use of power to promote equity and social justice in the classroom. The teachers identified a range of social-emotional skills, in particular social awareness and relationship skills, as important for refugee ELLs to develop. To help them, the teachers used various pedagogical methods, including explicit teaching, individualizing, creating a positive climate, and collaboration and support. However, the teachers' views of their refugee students' SEL and their self-reported pedagogical methods were largely deficit-oriented. Interpreting our findings within the existing literature from the critical perspective provides critical insights into teachers' perspectives and approaches to supporting refugee ELLs' SEL in early elementary grades.
OBJECTIVE: To summarise and discuss the association between telomerase activity and psychological stress, mental disorders and lifestyle factors. METHOD: A systematic review was carried out to identify prospective or retrospective studies and interventions published up to June 2015 that reported associations between telomerase activity and psychological stress, mental disorders and lifestyle factors. Electronic data bases of PubMed, ProQuest, CINAHL and Google Scholar were searched. RESULTS: Twenty six studies on humans measured telomerase activity in peripheral blood mononuclear cells (PBMCs) or leukocytes and examined its association with psychological stress, mental disorders and lifestyle factors. Of those studies, three reported significantly decreased telomerase activity in individuals under chronic psychological stress. Interestingly, one of the three studies found that acute laboratory psychological stress significantly increased telomerase activity. Nine studies reported mixed results on association between mental disorders and telomerase activity. Of the nine studies, five reported that major depressive disorder (MDD) was associated with significantly increased telomerase activity. In thirteen out of fourteen studies on lifestyle factors, it was reported that physical exercise, diet micronutrient supplementation, mindfulness meditation, Qigong practice or yoga mediation resulted in increase in telomerase activity. In addition, two studies on animal models showed that depression-like behaviour was associated with decreased hippocampus telomerase activity. Five animal studies showed that physical exercise increased telomerase activity by cell-type-specific and genotype-specific manners. CONCLUSION: Although multi-facet results were reported on the association between telomerase activity and psychological stress, mental disorders and lifestyle factors, there were some consistent findings in humans such as (1) decreased telomerase activity in individuals under chronic stress, (2) increased telomerase activity in individuals with MDD, and (3) increased telomerase activity in individuals under lifestyle interventions. Animal studies showed that physical exercise increased telomerase activity in specific cell-types. However, the exact mechanisms for the changes in telomerase activity have not been elucidated. We propose conglomerate models connecting chronic psychological stress, depression, mediation and physical exercise to telomerase activation. Several areas for future research are suggested.
OBJECTIVE: To summarise and discuss the association between telomerase activity and psychological stress, mental disorders and lifestyle factors. METHOD: A systematic review was carried out to identify prospective or retrospective studies and interventions published up to June 2015 that reported associations between telomerase activity and psychological stress, mental disorders and lifestyle factors. Electronic data bases of PubMed, ProQuest, CINAHL and Google Scholar were searched. RESULTS: Twenty six studies on humans measured telomerase activity in peripheral blood mononuclear cells (PBMCs) or leukocytes and examined its association with psychological stress, mental disorders and lifestyle factors. Of those studies, three reported significantly decreased telomerase activity in individuals under chronic psychological stress. Interestingly, one of the three studies found that acute laboratory psychological stress significantly increased telomerase activity. Nine studies reported mixed results on association between mental disorders and telomerase activity. Of the nine studies, five reported that major depressive disorder (MDD) was associated with significantly increased telomerase activity. In thirteen out of fourteen studies on lifestyle factors, it was reported that physical exercise, diet micronutrient supplementation, mindfulness meditation, Qigong practice or yoga mediation resulted in increase in telomerase activity. In addition, two studies on animal models showed that depression-like behaviour was associated with decreased hippocampus telomerase activity. Five animal studies showed that physical exercise increased telomerase activity by cell-type-specific and genotype-specific manners. CONCLUSION: Although multi-facet results were reported on the association between telomerase activity and psychological stress, mental disorders and lifestyle factors, there were some consistent findings in humans such as (1) decreased telomerase activity in individuals under chronic stress, (2) increased telomerase activity in individuals with MDD, and (3) increased telomerase activity in individuals under lifestyle interventions. Animal studies showed that physical exercise increased telomerase activity in specific cell-types. However, the exact mechanisms for the changes in telomerase activity have not been elucidated. We propose conglomerate models connecting chronic psychological stress, depression, mediation and physical exercise to telomerase activation. Several areas for future research are suggested.