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Six compounds were isolated from alcoholic extracts of Meconopsis quintuplinervia Regel.. On the basis of spectroscopic methods, their structures were identified as 8,9 -dihydroxy-1,5,6,10b-tetrahydro-2H-pyrrolo [ 2,1-a ] isoquinolin-3-one (1), o-methylflavinantine (2), amurine (3), tricin (4), luteolin (5) and β-sitosterol (6). Among them, compounds 1 and 4 were isolated from the plant for the first time.
Most species of <ce:italic>Gentianaceae</ce:italic> in Qinghai-Tibet Plateau are traditional Tibetan medicines which were used for stabilizing liver functions and improving the gallbladder. They were used for curing hepatitis, cholecystitis and other diseases. We have studied the chemical composition of 12 species of Gentianaceae and extracted 17 xanthone glycosides. Nine of them are new natural products. Pharmacological studies showed that xanthone C-glycosides is beneficial to the gallbladder and that xanthone O-glycosides is the effective component in curing hepatitis.