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Objective: To study the chemical constituents of the Tibetan medicine Caryopteris toroetii.; Method: The crude drug was extracted with 95% EtOH and isolated by repeatedly chromatographic methods. The structures of the isolated compounds were elucidated by spectral analysis.; Result: Six compounds were yielded and identified as: phenethyl cinnamide (1), 1-hydroxy-2, 3, 4, 5-tetramethoxy-xanthone (2), 1-hydroxy-2, 3, 5-trimethoxy-xanthone (3), (2S)-5-hydroxy-7-methoxyflavanone (4), 2', 4'-dihydroxydihydrochalcone (5) and rutin (6).; Conclusion: All the above compounds were obtained from C. toroetii for the first time.;
OBJECTIVE: To study the chemical constituents of Tibetan medicine Caryopteris toroetii.METHOD: The crude drug was extracted with 95% EtOH and isolated by repeated chromatographic methods. The structures of the isolated compounds were elucidated on the basis of spectral analysis.
RESULT: Two en-kaurene diterpenoid compounds: oridonin (1) and nodosin (2), were obtained from C. toroetii and their 1H and 13C-NMR data in CD3OD were reported for the first time.
CONCLUSION: The en-kaurene diterpenoid compounds were obtained from genus Caryopteris for the first time.