We examine the interdisciplinary nature of ethnobotany from a broad perspective and consider its application to the biology classroom and lab. The concept of biophilia and students' relationships with plants are integral components. Botanical nature journaling, discussion of diverse cultural practices, and collection of plants are used to encourage students' interest in local plants. Interwoven with these topics is a plant/microbial lab, which focuses on the local environment and the potential antimicrobial properties of plant parts.