The aim of this research was to consider the effectiveness of cognitive therapy based on mindfulness on reducing anxiety and depression of divorced women in Rasht city, Iran. The research method was experimental which was used of pretest posttest control group design. The statistical society included of 100 divorced women that referred to the Behzisti organization of Rasht in 2014-2015. They were Headed households. The average of their age was between 35-50 years old. Statistical sample was 30 individuals of women that gained at least one score lower than the average, in the scale of anxiety and depression. They are randomly replaced in two available groups with 15 individuals (experiment and control). Pretest was performed in both of groups. Then, cognitive therapy based on mindfulness was trained to the experiment group that was 8 sessions, each session had 120 minutes and each week had one session. The control group was not trained during this time. At the end, the posttest was performed on both groups in the same time and same situation. Data was collected by use of Beck depression and anxiety inventory. Data analyzes was performed by use of independent t-test in SPSS 20 software. The results showed that there was significant difference (p<0.05) between two groups in terms of depression and anxiety. Therefore, it can be concluded that cognitive therapy based on mindfulness was effective on reducing anxiety and depression of divorced women.