This pilot study evaluated the impact of mindfulness groups on 20 Latino middle school students who participated in 8-session structured groups using the Mindfulness-Based Stress Reduction for Teens curriculum. The participants’ scores on the Mindful Attention Awareness Scale; the Self-Compassion Scale; the Perceived Stress Scale; and the Depression, Anxiety, and Hostility subscales of the Symptom Check List–90–R were examined at 3 points in time. There were no significant changes during the baseline period. Following participation in the groups, the adolescents’ mindfulness and self-compassion scores significantly increased, and their perceived stress and depression significantly decreased.