Research in neurobiology supports use of spiritual techniques as a beneficial treatment for anxiety. Psychotherapy, including mindfulness CBT and meditation, has been shown to change brain structure. The amygdala-the brain structure responsible for processing emotion and anxiety-demonstrates plasticity, and the purpose of therapy may be to allow the cortex to establish more effective and efficient synaptic links with the amygdala. A main feature of spiritual approaches is changing one's focus of attention. Instead of worry, one focuses on peaceful thoughts, thoughts of helping others, etc. Research demonstrates that thought, meditation, and other manifestations of mind can alter the brain, sometimes in an enduring way. Few studies have addressed the neurobiological underpinnings of meditation. Limited evidence, however, suggests that brain changes occur during prolonged meditation and that meditation activates neural structures involved in attention and control of the autonomic nervous system.