Anti-oxidant components from the aerial parts of Asterothamnus centrali-asiaticus
PHYTOL Phytochemistry Letters
Format:
Journal Article
Publication Date:
Nov 30, 2015
Pages:
71 - 74
Sources ID:
103811
Collection:
Himalayan and Tibetan Medicine
Visibility:
Public (group default)
Abstract:
(Show)
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Two new phenolic acids (1⿿2) were isolated from the aerial parts of Asterothamnus centrali-asiaticus. Five knownphenolic acids (3⿿7) were also obtained from the title plant. 1⿿7 were evaluated for their anti-oxidant activity. 1⿿7 showed anti-oxidant activity with IC50 values ranging from 7.65 to 22.44 μg/mL.
Two new phenolic acids 2-hydroxy-5-[(6⿲-O-(E)-caffeoyl)-β-d-glucopyranosyl]-oxybenzoic acid (1) and 2-hydroxy-5-[(3⿲-O-(E)-caffeoyl)-β-d-glucopyranosyl]-oxybenzoic acid (2) were isolated from the aerial parts of Asterothamnus centrali-asiaticus, together with five known ones (3-7). Their structures were elucidated by extensive 1D and 2D NMR studies and HRESIMS investigations. The anti-oxidant activity of the isolates was evaluated through ABTS radical cation decolorization assay. The results showed that all of them exhibited anti-oxidant activity, and compound 7 was the most active compound with an IC50 value of 7.65 μg/mL.
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Two new phenolic acids (1⿿2) were isolated from the aerial parts of Asterothamnus centrali-asiaticus. Five knownphenolic acids (3⿿7) were also obtained from the title plant. 1⿿7 were evaluated for their anti-oxidant activity. 1⿿7 showed anti-oxidant activity with IC50 values ranging from 7.65 to 22.44 μg/mL.
Two new phenolic acids 2-hydroxy-5-[(6⿲-O-(E)-caffeoyl)-β-d-glucopyranosyl]-oxybenzoic acid (1) and 2-hydroxy-5-[(3⿲-O-(E)-caffeoyl)-β-d-glucopyranosyl]-oxybenzoic acid (2) were isolated from the aerial parts of Asterothamnus centrali-asiaticus, together with five known ones (3-7). Their structures were elucidated by extensive 1D and 2D NMR studies and HRESIMS investigations. The anti-oxidant activity of the isolates was evaluated through ABTS radical cation decolorization assay. The results showed that all of them exhibited anti-oxidant activity, and compound 7 was the most active compound with an IC50 value of 7.65 μg/mL.